NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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During which trimester is Propylthiouracil (PTU) recommended for treating hyperthyroidism in pregnancy?

  1. First

  2. Second

  3. Third

  4. All trimesters

The correct answer is: First

Propylthiouracil (PTU) is recommended for treating hyperthyroidism in pregnancy during the first trimester. This is because PTU is preferred over methimazole during the first trimester due to a lower risk of causing birth defects such as congenital malformations. However, after the first trimester, methimazole is preferred over PTU for the treatment of hyperthyroidism as it has a lower risk of hepatotoxicity for the mother. Therefore, PTU is recommended during the first trimester specifically for the safety of the developing fetus, making option A the correct choice.