NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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For what condition is Lomitapide (Juxtapid) approved?

  1. Elevated blood pressure

  2. Homozygous familial hypercholesterolemia

  3. Primary hypercholesterolemia

  4. Type 2 diabetes mellitus

The correct answer is: Homozygous familial hypercholesterolemia

Lomitapide (Juxtapid) is approved for the treatment of homozygous familial hypercholesterolemia. This condition is an inherited form of high cholesterol that is resistant to traditional cholesterol-lowering medications. Lomitapide works by inhibiting the synthesis of lipoproteins which helps to reduce the levels of low-density lipoprotein (LDL) cholesterol in the blood. It is important to note that this medication is specifically indicated for individuals with homozygous familial hypercholesterolemia and not for other conditions such as elevated blood pressure, primary hypercholesterolemia, or type 2 diabetes mellitus.

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