NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Second-generation antiandrogens can be used as a single treatment because they do not cause?

Androgen receptor upregulation
Decrease in testosterone production
Bone density loss
QT prolongation

The correct answer is: Androgen receptor upregulation

Second-generation antiandrogens, such as enzalutamide and apalutamide, are a type of hormone therapy used to treat prostate cancer. Unlike first-generation antiandrogens, second-generation antiandrogens do not cause androgen receptor upregulation. This means that they do not stimulate the growth of prostate cancer cells, making them a more effective treatment option. The other choices, including decrease in testosterone production, bone density loss, and QT prolongation, are potential side effects of second-generation antiandrogens, but they do not address the main reason why they can be used as a single treatment.