NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What are the adverse effects associated with dexmedetomidine?

  1. Hypo/hypertension, tachycardia

  2. Hyper/hypotension, bradycardia

  3. Hypotension, apnea

  4. Hypotension, bradycardia

The correct answer is: Hyper/hypotension, bradycardia

Dexmedetomidine is a selective alpha-2 adrenergic agonist typically used for sedation in the intensive care setting. One of the common adverse effects associated with dexmedetomidine is hemodynamic instability, including hypotension and bradycardia. This is due to its mechanism of action, which leads to reduced sympathetic outflow resulting in decreased blood pressure and heart rate. Therefore, option B, which includes hyper/hypotension and bradycardia, is the correct answer. Options A, C, and D are not the best choices because they do not accurately represent the common adverse effects of dexmedetomidine.

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