NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What bacteria is considered a Gram Negative Anaerobe?

  1. Propionibacterium acnes

  2. Neisseria spp.

  3. Bacteroides fragilis

  4. Mycoplasma pneumoniae

The correct answer is: Bacteroides fragilis

Gram-negative anaerobes are bacteria that do not require oxygen for growth and appear pink when subjected to a Gram stain test. Bacteroides fragilis is a well-known Gram-negative anaerobe commonly found in the gastrointestinal tract. Therefore, choice C is the correct answer. Propionibacterium acnes (choice A) is a Gram-positive anaerobe commonly associated with acne. Neisseria species (choice B) are Gram-negative aerobic bacteria known for causing infections such as meningitis and gonorrhea, but they are not anaerobes. Mycoplasma pneumoniae (choice D) is a unique bacterium that lacks a cell wall and is classified as a Gram-positive microorganism, but it is not an anaerobe.

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