NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What condition can cause angioedema and hyperkalemia as side effects?

  1. Using Sacubitril/Valsartan

  2. Taking high doses of beta-blockers

  3. Concomitant use of ACE inhibitors and ARBS

  4. None of the above

The correct answer is: Using Sacubitril/Valsartan

Angioedema is the swelling of the body's tissues due to a buildup of fluid, while hyperkalemia is high levels of potassium in the blood. Both of these conditions can be caused as side effects of using Sacubitril/Valsartan, which is a combination of a neprilysin inhibitor and an ARB. This medication is used to treat heart failure, and it is important to inform your doctor if you experience any symptoms of angioedema or hyperkalemia while taking it. High doses of beta-blockers and the concomitant use of ACE inhibitors and ARBs can also potentially cause these side effects, but they are not the primary cause in this scenario.

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