NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What does the management of HIV during pregnancy involve?

  1. Two NRTIs plus an INSTI

  2. One NNRTI plus two NRTIs

  3. Two NRTIs plus a boosted PI

  4. Both A and C

The correct answer is: Both A and C

Managing HIV during pregnancy involves the use of a combination of antiretroviral medications to prevent the transmission of the virus to the baby and to protect the health of the pregnant person. These medications, known as antiretroviral therapy (ART), typically involve a combination of two NRTIs (nucleotide reverse transcriptase inhibitors) and either an INSTI (integrase strand transfer inhibitor) or a boosted PI (protease inhibitor). Option A (Two NRTIs plus an INSTI) and Option C (Two NRTIs plus a boosted PI) are both correct combinations for ART during pregnancy. Option B (One NNRTI plus two NRTIs) is incorrect because while it may be a valid ART regimen for HIV management in general, it is not recommended specifically for pregnant individuals due to potential risks to the baby. Therefore, Option D (Both A and C) is the most comprehensive and accurate answer.

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