NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the dose limitation per cycle for Cisplatin to reduce the risk of its known toxicity?

  1. 50 mg/m2

  2. 75 mg/m2

  3. 100 mg/m2

  4. 125 mg/m2

The correct answer is: 100 mg/m2

Cisplatin is a chemotherapy medication used to treat various types of cancer. It works by preventing the growth and spread of cancer cells. However, it can also cause significant side effects, such as kidney damage and hearing loss. To reduce the risk of these known toxicities, the recommended dose limitation for Cisplatin is 100 mg/m2 per cycle. The other options may seem similar, but they are not recommended as they can increase the risk of toxicities without providing any additional benefit in treating cancer. Therefore, it is crucial to follow the recommended dose limit to ensure the maximum effectiveness and safety of Cisplatin treatment.