NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the formula to correct Phenytoin levels for albumin?

  1. total phenytoin measured / (0.2 x albumin) + 0.1

  2. multiply by 0.8

  3. 20 mEq/15 mL

  4. [(2 x diastolic pressure) + systolic pressure] /3

The correct answer is: total phenytoin measured / (0.2 x albumin) + 0.1

The correct formula to correct Phenytoin levels for albumin is total phenytoin measured divided by (0.2 times albumin) plus 0.1, as indicated in choice A. This formula takes into account the impact of albumin levels on the distribution of phenytoin in the body, allowing for a more accurate estimation of the corrected phenytoin level. Choices B, C, and D are not relevant to correcting Phenytoin levels for albumin. Choice B simply suggests multiplying by 0.8, which is not the correct method for adjusting phenytoin levels. Choices C and D are completely unrelated to correcting Phenytoin levels for albumin and do not provide the appropriate formula needed for this specific calculation.