NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the max dosing limit for pancreatic enzymes in CF patients?

Less than or equal to 10,000 units/kg/day
More than 20,000 units/kg/day
Exactly 5,000 units/kg/day
No limit specified

The correct answer is: Less than or equal to 10,000 units/kg/day

In cystic fibrosis (CF) patients, the maximum dosing limit for pancreatic enzymes is typically less than or equal to 10,000 units/kg/day. This dosage range is recommended to ensure effective enzyme replacement therapy without increasing the risk of adverse effects. It is important to dose pancreatic enzymes based on the individual patient’s needs and adjust the dose as necessary to achieve optimal therapeutic outcomes. Option B (More than 20,000 units/kg/day) exceeds the recommended maximum dose. Option C (Exactly 5,000 units/kg/day) is also incorrect as it does not align with the standard dosing limit for CF patients. Option D (No limit specified) is incorrect as there is indeed a recommended maximum dosing limit for pancreatic enzymes in CF patients.