NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What serum concentration is Digoxin dose adjusted to maintain in heart failure patients?

  1. < 2 ng/mL

  2. < 1.5 ng/mL

  3. < 1 ng/mL

  4. < 0.5 ng/mL

The correct answer is: < 1 ng/mL

In heart failure patients, Digoxin is a medication commonly used to help improve their symptoms and reduce hospitalizations. When monitoring Digoxin therapy, the therapeutic range of serum concentration is generally maintained below 1 ng/mL. This concentration range is crucial for optimizing the drug's effectiveness while minimizing the risk of toxicity. Therefore, option C, "< 1 ng/mL," is the correct answer.