NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Where does ADH (vasopressin) impact the kidney?

  1. Proximal tubule

  2. Loop of Henle

  3. Distal convoluted tubule

  4. Collecting duct

The correct answer is: Loop of Henle

ADH (vasopressin) impacts the kidney primarily in the collecting duct. It does so by increasing the permeability of the collecting duct to water, which allows for more water reabsorption back into the body, resulting in concentrated urine production. This action helps to regulate and maintain water balance in the body. The other options listed, such as the proximal tubule, distal convoluted tubule, and loop of Henle, play important roles in the overall process of urine formation and electrolyte regulation in the kidney, but they are not the primary sites of action for ADH.