NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which antidepressant is known to cause hepatotoxicity?

  1. Nefazodone

  2. Trazodone

  3. Sertraline

  4. Amitriptyline

The correct answer is: Nefazodone

Nefazodone is known to cause hepatotoxicity, also known as liver damage. It is important to be aware of this potential side effect and closely monitor liver function when taking this medication. Trazodone, sertraline, and amitriptyline are not associated with hepatotoxicity, however they may cause other side effects such as nausea, dizziness, and weight changes.

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