NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which is a CYP-1A2 inducer?

Clarithromycin
Carbamazepine
Amiodarone
Fluvoxamine

The correct answer is: Carbamazepine

Carbamazepine is a known CYP-1A2 inducer. This means that it can increase the metabolism and clearance of drugs that are metabolized by the CYP-1A2 enzyme. This is due to its ability to increase the production of this particular enzyme in the liver. A Clarithromycin is a CYP-3A inhibitor, which means it can decrease the metabolism and clearance of drugs that are metabolized by the CYP-3A enzyme. C: Amiodarone is a CYP-2C9 inhibitor, so it can decrease the metabolism and clearance of drugs that are metabolized by the CYP-2C9 enzyme. D: Fluvoxamine is a CYP-1A2 inhibitor, so it can decrease the metabolism and clearance of drugs that are metabolized by the CYP-1A2 enzyme. It is important to know which drugs are CYP-1A2 inducers, inhibitors, or neither, as they can affect how other medications are processed and can lead to potential drug interactions.