NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which medication is known to cause Drug-induced lupus erythematosus (DILE)?

  1. Ibuprofen

  2. Paracetamol

  3. Hydralazine

  4. Aspirin

The correct answer is: Hydralazine

Hydralazine is the correct answer. Drug-induced lupus erythematosus (DILE) is a form of lupus erythematosus that is caused by exposure to certain medications. Hydralazine, which is commonly used to treat high blood pressure, is known to induce lupus-like symptoms in some patients. It is important for healthcare providers to be aware of this potential side effect when prescribing hydralazine and to closely monitor patients for any signs or symptoms of DILE. Ibuprofen, Paracetamol, and Aspirin are not typically associated with causing drug-induced lupus erythematosus (DILE).

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