NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which medication is NOT known to worsen myasthenia gravis?

Magnesium Salts
Cladribine (Mavenclad)
Antibiotics: aminoglycosides
select antipsychotics

The correct answer is: Cladribine (Mavenclad)

Cladribine (Mavenclad) is not known to worsen myasthenia gravis. This medication is used to treat certain types of cancer and multiple sclerosis, but it does not have any known negative effects on myasthenia gravis. A Magnesium salts can worsen myasthenia gravis as they lower the amount of calcium released by nerve cells, which can lead to muscle weakness. C: Antibiotics such as aminoglycosides are known to worsen myasthenia gravis as they can interfere with the neurotransmitter acetylcholine, resulting in muscle weakness. D: Select antipsychotics can worsen myasthenia gravis by blocking dopamine receptors, which can affect muscle strength.