NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

Indomethacin is a non-steroidal anti-inflammatory drug (NSAID) that has a higher risk for central nervous system (CNS) effects compared to other NSAIDs. This is because it has a strong inhibitory effect on the production of prostaglandins, which are important for regulating pain and inflammation. This can lead to potential side effects such as headaches, dizziness, confusion, and drowsiness. While other NSAIDs may also have CNS effects, indomethacin has a higher risk and should be used with caution in patients with a history of CNS disorders. Ibuprofen, naproxen, and celecoxib have lower risks for CNS effects and are commonly used as first-line options for pain and inflammation.