NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

Anti-TNF Biologic DMARDs are known to carry a boxed warning for serious infections and malignancies. This warning is included because these medications work by suppressing the immune system, increasing the risk of infections and malignancies such as lymphoma. It is crucial for healthcare providers to monitor patients on these medications for signs and symptoms of infections and malignancies. Therefore, the correct answer is B.

Options A, C, and D are not the boxed warning associated with Anti-TNF Biologic DMARDs. Heart failure is a potential side effect of some DMARD medications, hepatotoxicity is a concern with certain medications, and seizures are not typically associated with Anti-TNF Biologic DMARDs.