NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

Question: 1 / 1820

For PAH, what is considered a positive response to vasoreactivity testing?

mPAP falls by at least 10 mmHg to less than 40 mmHg

In the context of PAH (Pulmonary Arterial Hypertension), a positive response to vasoreactivity testing is typically defined as a decrease in mean pulmonary arterial pressure (mPAP) by at least 10 mmHg to a level below 40 mmHg. This signifies that the pulmonary vasculature in the lungs is responding well to vasodilator therapy, which is crucial information in guiding the treatment approach for patients with PAH. It's important to recognize this specific criteria to identify patients who may benefit from therapies targeting vasodilation.

Options B, C, and D are not considered positive responses in vasoreactivity testing as they do not meet the standard criteria of a decrease by at least 10 mmHg to less than 40 mmHg, which is crucial in the assessment of pulmonary arterial hypertension.

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mPAP falls by at least 5 mmHg to less than 35 mmHg

mPAP falls by at least 15 mmHg to less than 45 mmHg

mPAP falls by at least 20 mmHg to less than 50 mmHg

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