NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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A major warning associated with ALK inhibitors is:

  1. QT prolongation

  2. New malignancies

  3. Acneiform rash

  4. Vascular occlusions

The correct answer is: QT prolongation

ALK inhibitors are a class of medications commonly used in the treatment of various cancers, such as non-small cell lung cancer. One of the major warnings associated with ALK inhibitors is QT prolongation. QT prolongation can lead to a type of irregular heartbeat that can be serious and may even lead to sudden death in some cases. Monitoring for QT prolongation and managing any risk factors is essential when using these medications to ensure patient safety.

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