NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Cyclosporine (Gengraf, Neoral) has a black box warning for:

  1. Increased risk of infection and nephrotoxicity

  2. Anaphylaxis

  3. QT prolongation

  4. Hyperlipidemia

The correct answer is: Increased risk of infection and nephrotoxicity

Cyclosporine (Gengraf, Neoral) is a medication used to prevent organ rejection after a transplant. As with many immuno-suppressive drugs, it can increase the risk of infection by suppressing the immune system. Nephrotoxicity, or damage to the kidneys, is also a potential side effect of this medication. While anaphylaxis, QT prolongation, and hyperlipidemia are all potential side effects of cyclosporine, they do not have a black box warning. A black box warning is the strongest warning that the FDA can require a medication to have and is reserved for serious and potentially life-threatening side effects. Therefore, option A is the correct answer.