NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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For severe cases of syphilis, the treatment recommended is:

doxy x14 days
Penicillin G benzathine IM weekly for 3 weeks
Penicillin G aqueous IV q4h x 10-14 days
azithromycin x1 or amoxicillin x7 days

The correct answer is: Penicillin G aqueous IV q4h x 10-14 days

For severe cases of syphilis, the recommended treatment is Penicillin G aqueous IV administered every 4 hours for a duration of 10-14 days. This regimen is the most effective in treating severe cases of syphilis as it ensures adequate and consistent levels of the antibiotic in the system to combat the infection. Penicillin G is the preferred treatment due to its effectiveness and ability to penetrate across the blood-brain barrier, which is essential for treating neurosyphilis or other severe forms of the disease. Option A, doxycycline for 14 days, is not the first-line treatment for severe syphilis. Option B, Penicillin G benzathine IM weekly for 3 weeks, is not the recommended regimen for severe cases. Option D, azithromycin for one day or amoxicillin for 7 days, is not as effective as the recommended Penicillin G aqueous IV regimen for treating severe cases of syphilis.