NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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How do you convert aminophylline to theophylline?

  1. Multiply by 1.2

  2. Divide by 0.8

  3. Multiply by 0.8

  4. Divide by 1.2

The correct answer is: Multiply by 0.8

Converting aminophylline to theophylline requires multiplying by 0.8. The conversion factor is 0.8 because the chemical structure of theophylline is 80% that of aminophylline. This means that 80% of the mass of aminophylline is theophylline. Dividing by 0.8, as suggested in option B, would actually result in a higher amount of theophylline than the original aminophylline, making it incorrect. Similarly, multiplying by 1.2 (option A) or dividing by 1.2 (option D) would also result in incorrect values.