NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

Disable ads (and more) with a membership for a one time $4.99 payment

Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

Practice this question and more.


How is % ionization calculated for a weak acid?

  1. 100/(1+10^(pKa-pH))

  2. 100*(1+10^(pKa-pH))

  3. 100/(1-10^(pKa-pH))

  4. 100*(1-10^(pKa-pH))

The correct answer is: 100/(1+10^(pKa-pH))

To calculate the percent ionization for a weak acid, you can use the formula: % ionization = 100/(1+10^(pKa-pH)). This formula takes into account the acid dissociation constant (pKa) and the pH of the solution. Option A is correct because it correctly represents the relationship between the pKa, pH, and percent ionization for a weak acid. The percent ionization increases as the pH of the solution decreases (becomes more acidic) and as the difference between the pKa and pH values increases. Options B, C, and D are incorrect because they do not accurately represent the formula for calculating the percent ionization of a weak acid.