NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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How is % ionization calculated for a weak base?

  1. 100/(1+10^(pH-pKa))

  2. 100*[1 + [10^(pKa-pH)]]

  3. 100*(1+10^(pKa-pH))

  4. 100*[1 + [10^-(pH-pKa)]]

The correct answer is: 100/(1+10^(pH-pKa))

The correct formula to calculate the percent ionization for a weak base is 100/(1+10^(pH-pKa)). This formula takes into account the pH, which is a measure of how acidic or basic a solution is, and the pKa, which is the negative logarithm of the acid dissociation constant of the weak base. By using this formula, you can determine the percentage of the weak base that has been ionized at a particular pH level.