NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Rifaximin is NOT effective for?

Systemic infections
Traveler's diarrhea
Hepatic encephalopathy
IBS-D

The correct answer is: Systemic infections

Rifaximin is an antibiotic that is primarily used to treat bacterial infections. It works by stopping the growth and spread of bacteria. However, it is not effective against systemic infections because it is not designed to reach high enough levels in the bloodstream to combat infections throughout the body. This is why options B, C, and D are incorrect as they are all conditions that stem from bacterial infections in specific areas (traveler's diarrhea, liver, and digestive tract, respectively). Rifaximin is only effective for infections and conditions that are localized to the digestive tract, such as IBS-D. It is not designed or intended to treat infections in other parts of the body.