NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Under which condition should the Friedewald equation not be used?

If TG < 200
If HDL > 60
If TG > 400
If LDL < 100

The correct answer is: If TG > 400

The Friedewald equation should not be used if the level of triglycerides (TG) is greater than 400 mg/dL. This is because at such high levels, it can lead to inaccurate calculations of LDL cholesterol. LDL cholesterol is an important marker for cardiovascular risk, and its accurate measurement is crucial for proper diagnosis and treatment. Therefore, it is important to consider other methods for calculating LDL cholesterol, such as direct measurement, if TG levels are very high. Option A is incorrect because a TG level of less than 200 mg/dL is actually a requirement for using the Friedewald equation. Option B is incorrect because a HDL level higher than 60 mg/dL does not affect the accuracy of the Friedewald equation. Option D is incorrect because a LDL level lower than 100 mg/dL falls within the normal range and is not a cause for concern when using the Friedewald equation.