NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Warfarin is contraindicated in which of the following conditions?

  1. Mechanical heart valve

  2. Pregnancy (except in cases of mechanical heart valve)

  3. High cholesterol

  4. Diabetes

The correct answer is: Pregnancy (except in cases of mechanical heart valve)

Warfarin is contraindicated in pregnancy, except in cases of mechanical heart valves, because it crosses the placenta and can lead to birth defects or bleeding complications in the developing fetus. For this reason, it is important to avoid warfarin during pregnancy whenever possible. Options A, C, and D are not contraindications for warfarin use.

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