NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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What adverse effect is associated with Sodium zirconium cyclosilicate (Lokelma)?

Hyperkalemia
Hypomagnesemia
Binds other drugs
High blood pressure

The correct answer is: Binds other drugs

Sodium zirconium cyclosilicate (Lokelma) is a non-absorbed, highly selective potassium-binding agent that is used for the treatment of hyperkalemia. One of the advantages of Lokelma is that it has minimal systemic absorption and does not affect the levels of magnesium or calcium in the body, making hypomagnesemia (Choice B) an incorrect option. Additionally, Lokelma does not cause hyperkalemia (Choice A) because it is actually used to lower high potassium levels in the blood. While high blood pressure (Choice D) can be a side effect of some medications, Lokelma is not known to cause hypertension. The correct answer, Choice C, states that Lokelma binds other drugs, which is an important consideration for pharmacists to avoid drug interactions when administering medications alongside Lokelma.