NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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What antidote is used for acetaminophen overdose?

Atropine
N-Acetylcysteine (NAC, Acetadote)
Methylene blue
Flumazenil

The correct answer is: N-Acetylcysteine (NAC, Acetadote)

N-Acetylcysteine (NAC, Acetadote) is the antidote used for acetaminophen overdose. Acetaminophen overdose can lead to hepatotoxicity and potentially fatal liver damage. NAC works by replenishing hepatic stores of glutathione, which is depleted in cases of acetaminophen overdose. This helps prevent the formation of the toxic metabolite responsible for liver damage. Atropine is used for the treatment of organophosphate poisoning, methylene blue is used as an antidote for methemoglobinemia, and flumazenil is a benzodiazepine antagonist used for benzodiazepine overdose.