NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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What are common adverse effects of Anastrozole and Letrozole?

Increased liver function tests
Hot flashes/night sweats and arthralgia/myalgia
Injection site pain
Gynecomastia and bone pain

The correct answer is: Hot flashes/night sweats and arthralgia/myalgia

Hot flashes/night sweats and arthralgia/myalgia are common adverse effects of both Anastrozole and Letrozole because they belong to a class of medications called aromatase inhibitors. These medications work by lowering estrogen levels in the body, which can cause hot flashes and joint/muscle pain. Increased liver function tests (A) can occur, but it is not a common adverse effect of these medications. Injection site pain (C) is not relevant as Anastrozole and Letrozole are oral medications. Gynecomastia (D) and bone pain (D) are not common adverse effects of these medications and are not related to their mechanism of action. Therefore, the other options are incorrect as they are not common adverse effects of Anastrozole and Letrozole.