NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

What class of drug is Voclosporin?

1. Calcineurin Inhibitor

2. Sphingosine 1-phosphate Receptor Modulators

3. Pyrimidine Synthesis Inhibitor

4. Potassium Channel Blocker

The correct answer is: Calcineurin Inhibitor

Voclosporin belongs to the class of drugs known as Calcineurin Inhibitors. This class of drugs works by inhibiting the enzyme calcineurin, which plays a crucial role in the activation of T-lymphocytes in the immune system. By inhibiting this enzyme, calcineurin inhibitors like voclosporin help prevent the rejection of transplanted organs by suppressing the immune response. The other options are not correct: - Sphingosine 1-phosphate Receptor Modulators are a different class of drugs used in the treatment of multiple sclerosis. - Pyrimidine Synthesis Inhibitors are a class of drugs used in chemotherapy to inhibit the production of DNA and RNA in cancer cells. - Potassium Channel Blockers are medications that affect the movement of potassium ions across cell membranes and are used in the treatment of conditions like arrhythmias.