NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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What class of drugs does atorvastatin belong to, based on its metabolism?

CYP-3A4 substrates
CYP-1A2 substrates
CYP-2C9 inhibitors
CYP-3A4 inducers

The correct answer is: CYP-3A4 substrates

Atorvastatin belongs to the class of drugs known as CYP-3A4 substrates based on its metabolism. This means that it is metabolized by the enzyme CYP-3A4 in the liver, which plays a crucial role in drug metabolism. While CYP-1A2 substrates and CYP-2C9 inhibitors are also classes of drugs that are metabolized by specific enzymes, they are not the correct class for atorvastatin. Similarly, CYP-3A4 inducers are drugs that can increase the activity of CYP-3A4, which can alter the metabolism of other medications. However, atorvastatin is not classified as a CYP-3A4 inducer. Thus, the correct answer is A CYP-3A4 substrates.