NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What does 'ACHES' acronym stand for regarding severe & rare adverse effects of estrogen?

  1. Appetite changes, Chest pain, Headaches, Eye problems, Swelling

  2. Abdominal pain, Chest pain, Headaches, Eye problems, Swelling or sudden leg pain

  3. Anxiety, Constipation, Heartburn, Eye strain, Sleep disturbances

  4. None of the above

The correct answer is: Abdominal pain, Chest pain, Headaches, Eye problems, Swelling or sudden leg pain

The lettered options in this question represent different acronyms that could potentially spell out 'ACHES'. Option A does not contain 'Abdominal pain' which is a common adverse effect of estrogen. Option C does not correctly spell out the acronym and contains symptoms that are not commonly associated with the adverse effects of estrogen. Therefore, option B is the correct answer as it contains all the correct symptoms and correctly spells out the acronym 'ACHES'.