NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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What does an Equivalence trial attempt to demonstrate?

The new treatment is better than the old treatment
The new treatment is worse than the old treatment
The new treatment has roughly the same effect as the old treatment
The effect of the new treatment is unknown compared to the old treatment

The correct answer is: The new treatment has roughly the same effect as the old treatment

An Equivalence trial aims to demonstrate that the new treatment has roughly the same effect as the old treatment. This type of trial is designed to show that the difference in effectiveness between the new and old treatments is within a pre-specified margin of equivalence. By choosing option C, it correctly reflects the goal and purpose of an equivalence trial. Options A and B are incorrect because an equivalence trial is not focused on proving that the new treatment is better or worse than the old treatment; it is specifically focused on demonstrating that the two treatments have similar effects. Option D is also incorrect because equivalence trials are conducted precisely to determine if there is an equivalent effect between the new and old treatments, rather than leaving the comparison as unknown.