NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What does ospemifene treat?

  1. Mild vaginal dryness

  2. Dyspareunia and moderate-severe vaginal dryness

  3. Osteoporosis

  4. Hot flashes

The correct answer is: Dyspareunia and moderate-severe vaginal dryness

Ospemifene is a selective estrogen receptor modulator (SERM) that is indicated for the treatment of dyspareunia and moderate to severe vaginal dryness associated with menopause. It works by acting as an estrogen agonist on the vaginal epithelium, leading to an increase in vaginal secretions and reduction of symptoms such as dryness and pain during intercourse. Therefore, the correct answer is B. Option A is incorrect because ospemifene is not indicated for mild vaginal dryness. Option C is incorrect because ospemifene is not used for the treatment of osteoporosis. Option D is incorrect because ospemifene is not indicated for treating hot flashes.