NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

Disable ads (and more) with a membership for a one time $4.99 payment

Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

Practice this question and more.

What does Probenecid do besides its main action as a Uricosuric?

Decreases insulin levels
Increases beta-lactam levels
Lowers cholesterol
Reduces sugar absorption

The correct answer is: Increases beta-lactam levels

Probenecid is a medication known for its main action as a uricosuric agent, which means it increases the excretion of uric acid in the urine. In addition to this primary effect, Probenecid is also known to increase beta-lactam levels. This is important to note because Probenecid can inhibit the renal tubular secretion of some antibiotics, such as penicillins, leading to higher serum levels of these medications when they are taken concomitantly with Probenecid. This interaction can be beneficial in certain situations where higher antibiotic levels are desired for increased efficacy. The other options are incorrect: A. Probenecid does not decrease insulin levels. C. Probenecid does not lower cholesterol. D. Probenecid does not reduce sugar absorption.