NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What does trituration involve?

  1. Increasing the water content of a substance

  2. Mixing thoroughly or making a product homogenous

  3. Adding colors to a compound

  4. Storing medications under refrigeration

The correct answer is: Mixing thoroughly or making a product homogenous

Trituration involves mixing thoroughly or making a product homogenous. In pharmaceutical compounding, trituration specifically refers to the process of mixing a powder with a mortar and pestle to ensure uniform distribution of the drug throughout the mixture. This process helps to achieve consistency in drug concentration and improve the overall quality of the final product. Increasing the water content of a substance (Option A) is not related to trituration. Adding colors to a compound (Option C) is associated with coloring agents and not with the process of trituration. Storing medications under refrigeration (Option D) pertains to proper storage conditions and is not the primary purpose of trituration.

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