NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What drug is used for HER2 overexpressed breast tumor treatment?

  1. Trastuzumab

  2. Tamoxifen

  3. Anastrozole

  4. Metformin

The correct answer is: Trastuzumab

Trastuzumab is a monoclonal antibody that is specifically designed to target HER2 overexpressing breast tumors. It works by binding to the HER2 protein and inhibiting its signaling, leading to slower tumor growth and improved survival rates. Tamoxifen and Anastrozole are both hormonal therapies commonly used for estrogen receptor positive breast tumors, while Metformin is a medication used for managing blood sugar levels in patients with diabetes. None of these options are effective for HER2 overexpressed tumors and could potentially cause harm if used for this type of breast cancer. Therefore, Trastuzumab is the only drug that is recommended for treatment of HER2 overexpressed breast tumors.