NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What indicates dehydration in the context of AKI?

  1. BUN:SCr ratio > 20:1 plus decreased urine output

  2. High blood pressure

  3. High blood sugar levels

  4. Increased urine output

The correct answer is: BUN:SCr ratio > 20:1 plus decreased urine output

In the context of AKI (acute kidney injury), dehydration is indicated by a BUNSCr ratio greater than 20:1 in conjunction with decreased urine output. The ratio refers to the levels of blood urea nitrogen and serum creatinine, which may become elevated when the body is dehydrated. Additionally, decreased urine output can be a sign of dehydration as the kidneys conserve water in response to a lack of fluids. High blood pressure and high blood sugar levels are not specific indicators of dehydration in this context, while increased urine output is actually a sign of hydration rather than dehydration.

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