NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is a common side effect of prostaglandin analogs used for glaucoma?

  1. Decreased pigmentation of iris/eyelashes

  2. Shortened eyelash length

  3. Darkening of iris, eyelid skin, and eyelashes

  4. Decreased eyelash growth

The correct answer is: Darkening of iris, eyelid skin, and eyelashes

Prostaglandin analogs used for glaucoma commonly cause darkening of the iris, eyelid skin, and eyelashes. This side effect is known as hyperpigmentation and is a well-documented adverse effect of this class of medications. The darkening occurs due to increased melanin production in the cells of the affected tissues. This is why choice C is the correct answer. Choices A, B, and D are not correct as they do not accurately represent the common side effect associated with prostaglandin analogs used for glaucoma.

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