NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is a common side effect of testosterone therapy in males?

  1. Hypertension

  2. Male pattern baldness

  3. Hypothyroidism

  4. Increased insulin sensitivity

The correct answer is: Male pattern baldness

Testosterone therapy in males commonly leads to male pattern baldness as a side effect. Testosterone can be converted into dihydrotestosterone (DHT), a hormone responsible for hair loss or male pattern baldness in genetically predisposed individuals. Therefore, it is important to discuss the potential side effects of testosterone therapy, including male pattern baldness, with patients prior to initiating treatment. Regarding the other options: A. Hypertension: Testosterone therapy is not typically associated with hypertension. C. Hypothyroidism: Testosterone therapy does not commonly cause hypothyroidism. D. Increased insulin sensitivity: Testosterone therapy may actually improve insulin sensitivity rather than increase it.