NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is a common toxicity of VEGF inhibitors like Bevacizumab?

  1. Neuropathy

  2. Hair loss

  3. Proteinuria

  4. Diarrhea

The correct answer is: Proteinuria

VEGF inhibitors like Bevacizumab are commonly associated with proteinuria. This side effect occurs due to the alteration of the filtration function of the kidneys. Proteinuria refers to the presence of excess protein in the urine, which can be an indication of kidney damage. Monitoring for proteinuria is important when patients are receiving VEGF inhibitors to prevent potential kidney-related complications. While neuropathy, hair loss, and diarrhea are side effects associated with other medications, they are not commonly linked to VEGF inhibitors like Bevacizumab.

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