NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

What is a contraindication for using Bremelanotide (Vyleesi)?

1. Controlled hypertension

2. Uncontrolled hypertension or known cardiovascular disease

3. Diabetes

4. Hyperlipidemia

The correct answer is: Uncontrolled hypertension or known cardiovascular disease

Bremelanotide (Vyleesi) is a medication used for the treatment of premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD). It is a melanocortin receptor agonist that works by activating the melanocortin receptors in the central nervous system. The correct answer is B, which is an important contraindication for using Bremelanotide (Vyleesi). Uncontrolled hypertension or known cardiovascular disease is a contraindication due to the potential risk of increasing blood pressure and cardiovascular events associated with the use of Bremelanotide. Therefore, it is crucial to screen patients for hypertension and cardiovascular disease before initiating treatment with Bremelanotide to ensure patient safety. Options A, C, and D are not direct contraindications for using Bremelanotide (Vyleesi). Controlled hypertension may not necessarily preclude the use of Bremelanotide as long as blood pressure is carefully monitored. Diabetes and hyperlipidemia are not specific contraindications for using Bremelanotide and do not pose the same risk as uncontrolled hypertension or known cardiovascular disease.