NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is a contraindication for the use of Colesevelam (Welchol)?

  1. TG > 300

  2. TG > 500

  3. Bowel obstruction

  4. Complete biliary obstruction

The correct answer is: Bowel obstruction

A contraindication is a specific situation in which a drug, procedure, or surgery should not be used because it may be harmful. In this case, the correct answer is C because bowel obstruction, which is the blockage of the intestinal tract, can cause complications with the use of Colesevelam. Option A and B, both TG > 300 and TG > 500 refer to high levels of triglycerides, which is not a contraindication for the use of Colesevelam. Option D, complete biliary obstruction, is also not a contraindication for the use of Colesevelam; however, it may affect the absorption of the medication. It is important to note that only option C is a contraindication for the use of Colesevelam.

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