NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is Febuxostat's black box warning related to?

  1. Increased risk of infection

  2. Increased risk of CV death

  3. Increased risk of cancer

  4. Increased risk of kidney failure

The correct answer is: Increased risk of CV death

Febuxostat's black box warning is related to an increased risk of cardiovascular (CV) death. This means that patients taking Febuxostat may have a higher chance of experiencing death due to a heart attack or other CV events. It is important for patients to be aware of this risk and to discuss with their doctor any potential alternative options for treatment. The other options are incorrect because Febuxostat is not associated with an increased risk of infection, cancer, or kidney failure.

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