NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is Lesinurad used for?

  1. Inhibiting reabsorption of sodium

  2. Increasing uric acid excretion

  3. Treating anaphylactic reactions

  4. Blocking uric acid production

The correct answer is: Increasing uric acid excretion

Lesinurad is a medication used to treat hyperuricemia (elevated levels of uric acid in the blood) associated with gout. It works by inhibiting the activity of the organic anion transporter that reabsorbs uric acid in the kidneys, thereby increasing uric acid excretion in the urine. Option A, inhibiting reabsorption of sodium, is incorrect because Lesinurad does not affect sodium levels. Option C, treating anaphylactic reactions, is incorrect because Lesinurad is not used for the treatment of allergic reactions. Option D, blocking uric acid production, is incorrect because Lesinurad works by increasing uric acid excretion, not by blocking its production in the body.

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