NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

What is the conversion ratio of IV to PO for Metoprolol tartrate?

1. 1:1

2. 1:2

3. 1:2.5

4. 1:3

The correct answer is: 1:2.5

When converting a medication from intravenous (IV) to oral (PO) administration, it is important to consider the bioavailability of the drug. In the case of Metoprolol tartrate, the conversion ratio from IV to PO is 1:2.5. This means that for every 1 mg of Metoprolol tartrate given intravenously, the equivalent dose for oral administration would be 2.5 mg. It is crucial for pharmacists and healthcare providers to be aware of these conversion ratios to ensure patients receive the appropriate dosage when transitioning from IV to PO administration. Option A (1:1) is incorrect because the conversion ratio for Metoprolol tartrate is not 1:1. Option B (1:2) is also incorrect, as the correct conversion ratio is 1:2.5. Option D (1:3) is not the correct conversion ratio for Metoprolol tartrate. Therefore, the correct answer is C, 1:2.5.