NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

What is the equivalent dose of Simvastatin in statin equivalent doses?

1. Pitavastatin 2 mg

2. Rosuvastatin 5 mg

3. Atorvastatin 10 mg

4. Simvastatin 20 mg

The correct answer is: Simvastatin 20 mg

The equivalent dose of Simvastatin in statin equivalent doses is 20 mg. This is because Simvastatin has a simvastatin-equivalent dose of 1, meaning that for every 1 mg of Simvastatin, there is 1 mg of other statin drugs. Therefore, to find the equivalent dose of other statin drugs in comparison to Simvastatin, you would multiply their dosage by their simvastatin-equivalent dose. In this case, 2 mg of Pitavastatin would be equivalent to 2 mg of Simvastatin, 5 mg of Rosuvastatin would be equivalent to 5 mg of Simvastatin, and 10 mg of Atorvastatin would be equivalent to 10 mg of Simvastatin. This shows that the equivalent dose of Simvastatin is the same as its actual dose, 20 mg. Option A, Pitavastatin 2 mg, is incorrect because it is only equivalent to 2 mg of Simvastatin, not the equivalent dose. Option B, Rosuvastatin 5 mg, is incorrect for the same reason as option A. Option C, Atorvast