NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the first-line treatment for Acute Otitis Media (AOM)?

Azithromycin, clarithromycin
Amoxicillin, amoxicillin/clavulanate
Cefdinir, cefuroxime
Doxycycline, micafungin

The correct answer is: Amoxicillin, amoxicillin/clavulanate

Acute Otitis Media (AOM) is an infection of the middle ear, usually caused by a bacterial or viral infection. Amoxicillin and amoxicillin/clavulanate are the recommended first-line treatment for AOM, as they are effective against the most common bacteria that cause AOM. Option A includes azithromycin and clarithromycin, which are typically used for respiratory infections but are not as effective for AOM. Option C and D are both antibiotics, but they are not as effective against AOM as amoxicillin and amoxicillin/clavulanate. Therefore, the correct answer is B.