NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the goal hemoglobin level after a blood transfusion in sickle cell patients?

No higher than 10 g/dL
Exactly 12 g/dL
No higher than 15 g/dL
At least 8 g/dL

The correct answer is: No higher than 10 g/dL

Sickle cell patients have a genetic disorder that causes abnormal hemoglobin, which can lead to complications such as anemia and organ damage. A blood transfusion is often used to help manage these complications by providing healthy red blood cells. However, too much hemoglobin can lead to increased blood viscosity and further complications. Therefore, it is important to carefully monitor the hemoglobin levels in sickle cell patients after a blood transfusion. Option A, no higher than 10 g/dL, is the safest range to aim for to avoid potential complications. Option B, exactly 12 g/dL, may be too high for some patients and can increase the risk of complications. Option C, no higher than 15 g/dL, is also too high and can potentially worsen the patient's condition. Option D, at least 8 g/dL, may be too low and could indicate insufficient improvement in the patient's anemia.